Professor Judea Pearl won the 2011 Turing Award "for fundamental contributions to artificial intelligence through the development of a calculus for probabilistic and causal reasoning." This book contains the original articles that led to the award, as well as other seminal works, divided into four parts: heuristic search, probabilistic reasoning, causality, first period (1988-2001), and causality, recent period (2002-2020). Each of these parts starts with an introduction written by Judea Pearl. The volume also contains original, contributed articles by leading researchers that analyze, extend, or assess the influence of Pearl's work in different fields: from AI, Machine Learning, and Statistics to Cognitive Science, Philosophy, and the Social Sciences. The first part of the volume includes a biography, a transcript of his Turing Award Lecture, two interviews, and a selected bibliography annotated by him.